2NQC

Crystal structure of ig-like domain 23 from human filamin C

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Filamin-C	polymer	138	13922.6	1	UniProt (Q14315) Pfam (PF00630)	Homo sapiens (human)	Gamma-filamin, Filamin-2, Protein FLNc, Actin-binding- like protein, ABP-L, ABP-280-like protein
2	B (A)	NICKEL (II) ION	non-polymer		58.7	1	Chemie (NI)
3	C, D (A)	IMIDAZOLE	non-polymer		69.1	2	Chemie (IMD)
4	E, F (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	G (A)	water	water		18.0	56	Chemie (HOH)

Sequence modifications

A: 2475 - 2578 (UniProt: Q14315)

PDB	External Database	Details
Gly 2441	-	expression tag
Ser 2442	-	expression tag
His 2443	-	expression tag
Met 2444	-	expression tag
Ala 2445	-	expression tag
Ser 2446	-	expression tag
Met 2447	-	expression tag
Thr 2448	-	expression tag
Gly 2449	-	expression tag
Gly 2450	-	expression tag
Gln 2451	-	expression tag
Gln 2452	-	expression tag
Met 2453	-	expression tag
Gly 2454	-	expression tag
Arg 2455	-	expression tag
Gly 2456	-	expression tag
Ser 2457	-	expression tag
Gly 2458	-	expression tag
Ser 2459	-	expression tag
His 2460	-	expression tag
Met 2461	-	expression tag
Ala 2462	-	expression tag
Ser 2463	-	expression tag
Met 2464	-	expression tag
Thr 2465	-	expression tag
Gly 2466	-	expression tag
Gly 2467	-	expression tag
Gln 2468	-	expression tag
Gln 2469	-	expression tag
Met 2470	-	expression tag
Gly 2471	-	expression tag
Arg 2472	-	expression tag
Gly 2473	-	expression tag
Ser 2474	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	13922.6
Non-Polymers*	Number of molecules	5
	Total formula weight	381.1
All*	Total formula weight	14303.6

*Water molecules are not included.