2NQ6
Crystal structure of human methionine aminopeptidase type 1 in complex with 3-tert-Butoxycarbonylaminopyridine-2-carboxylic acid thiazole-2-ylamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Methionine aminopeptidase 1 | polymer | 329 | 36935.9 | 1 | UniProt (P53582) Pfam (PF00557) In PDB | Homo sapiens (human) | MetAP 1; MAP 1; Peptidase M 1 |
2 | A | COBALT (II) ION | non-polymer | 58.9 | 3 | Chemie (CO) | |||
3 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
4 | A | TERT-BUTYL {2-[(1,3-THIAZOL-2-YLAMINO)CARBONYL]PYRIDIN-3-YL}CARBAMATE | non-polymer | 320.4 | 1 | Chemie (HM4) | |||
5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
6 | water | water | 18.0 | 340 | Chemie (HOH) |
Sequence modifications
A: 90 - 393 (UniProt: P53582)
PDB | External Database | Details |
---|---|---|
Met 65 | - | expression tag |
Gly 66 | - | expression tag |
Ser 67 | - | expression tag |
Ser 68 | - | expression tag |
His 69 | - | expression tag |
His 70 | - | expression tag |
His 71 | - | expression tag |
His 72 | - | expression tag |
His 73 | - | expression tag |
His 74 | - | expression tag |
Ser 75 | - | expression tag |
Ser 76 | - | expression tag |
Gly 77 | - | expression tag |
Leu 78 | - | expression tag |
Val 79 | - | expression tag |
Pro 80 | - | expression tag |
Arg 81 | - | expression tag |
Gly 82 | - | expression tag |
Ser 83 | - | expression tag |
His 84 | - | expression tag |
Met 85 | - | expression tag |
Leu 86 | - | expression tag |
Glu 87 | - | expression tag |
Asp 88 | - | expression tag |
Pro 89 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 36935.9 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 629.3 | |
All* | Total formula weight | 37565.3 |