2NPU
The solution structure of the rapamycin-binding domain of mTOR (FRB)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | FKBP12-rapamycin complex-associated protein | polymer | 126 | 15361.4 | 1 | UniProt (P42345) Pfam (PF08771) | Homo sapiens (human) | FK506-binding protein 12-rapamycin complex-associated protein 1, Rapamycin target protein, RAPT1, Mammalian target of rapamycin, mTOR |
Sequence modifications
A: 2015 - 2114 (UniProt: P42345)
| PDB | External Database | Details |
|---|---|---|
| Met 1989 | - | expression tag |
| Ser 1990 | - | expression tag |
| Tyr 1991 | - | expression tag |
| Tyr 1992 | - | expression tag |
| His 1993 | - | expression tag |
| His 1994 | - | expression tag |
| His 1995 | - | expression tag |
| His 1996 | - | expression tag |
| His 1997 | - | expression tag |
| His 1998 | - | expression tag |
| Asp 1999 | - | linker |
| Tyr 2000 | - | linker |
| Asp 2001 | - | linker |
| Ile 2002 | - | linker |
| Pro 2003 | - | linker |
| Thr 2004 | - | linker |
| Thr 2005 | - | linker |
| Glu 2006 | - | linker |
| Asn 2007 | - | linker |
| Leu 2008 | - | linker |
| Tyr 2009 | - | linker |
| Phe 2010 | - | linker |
| Gln 2011 | - | linker |
| Gly 2012 | - | linker |
| Ala 2013 | - | linker |
| Met 2014 | - | linker |
| Pro 2020 | Ala 2020 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15361.4 | |
| All* | Total formula weight | 15361.4 |
