2NPU
The solution structure of the rapamycin-binding domain of mTOR (FRB)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | FKBP12-rapamycin complex-associated protein | polymer | 126 | 15361.4 | 1 | UniProt (P42345) Pfam (PF08771) In PDB | Homo sapiens (human) | FK506-binding protein 12-rapamycin complex-associated protein 1, Rapamycin target protein, RAPT1, Mammalian target of rapamycin, mTOR |
Sequence modifications
A: 2015 - 2114 (UniProt: P42345)
PDB | External Database | Details |
---|---|---|
Met 1989 | - | expression tag |
Ser 1990 | - | expression tag |
Tyr 1991 | - | expression tag |
Tyr 1992 | - | expression tag |
His 1993 | - | expression tag |
His 1994 | - | expression tag |
His 1995 | - | expression tag |
His 1996 | - | expression tag |
His 1997 | - | expression tag |
His 1998 | - | expression tag |
Asp 1999 | - | linker |
Tyr 2000 | - | linker |
Asp 2001 | - | linker |
Ile 2002 | - | linker |
Pro 2003 | - | linker |
Thr 2004 | - | linker |
Thr 2005 | - | linker |
Glu 2006 | - | linker |
Asn 2007 | - | linker |
Leu 2008 | - | linker |
Tyr 2009 | - | linker |
Phe 2010 | - | linker |
Gln 2011 | - | linker |
Gly 2012 | - | linker |
Ala 2013 | - | linker |
Met 2014 | - | linker |
Pro 2020 | Ala 2020 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 15361.4 | |
All* | Total formula weight | 15361.4 |