2NPT

Crystal Structure of the complex of human mitogen activated protein kinase kinase 5 phox domain (MAP2K5-phox) with human mitogen activated protein kinase kinase kinase 2 phox domain (MAP3K2-phox)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Dual specificity mitogen-activated protein kinase kinase 5	polymer	106	11941.5	2	UniProt (Q13163) Pfam (PF00564) In PDB	Homo sapiens (human)	MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5
2	B, D	Mitogen-activated protein kinase kinase kinase 2	polymer	100	11535.4	2	UniProt (Q9Y2U5) Pfam (PF00564) In PDB	Homo sapiens (human)	MAPK/ERK kinase kinase 2, MEK kinase 2, MEKK 2
3		water	water		18.0	320	Chemie (HOH)

Sequence modifications

A, C: 5 - 108 (UniProt: Q13163)

PDB	External Database	Details
Ser 3	-	cloning artifact
Met 4	-	cloning artifact

B, D: 26 - 123 (UniProt: Q9Y2U5)

PDB	External Database	Details
Ser 24	-	cloning artifact
Met 25	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	46953.8
All*	Total formula weight	46953.8

*Water molecules are not included.