2NPS
Crystal Structure of the Early Endosomal SNARE Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vesicle-associated membrane protein 4 | polymer | 74 | 8687.8 | 1 | UniProt (O70480) Pfam (PF00957) | Mus musculus (house mouse) | VAMP-4 |
| 2 | B (B) | Syntaxin 13 | polymer | 71 | 8149.2 | 1 | UniProt (O70319) Pfam (PF05739) UniProt (by SIFTS) (G3V7P1) | Rattus norvegicus (Norway rat) | |
| 3 | C (C) | Vesicle transport through interaction with t-SNAREs homolog 1A | polymer | 81 | 9548.8 | 1 | UniProt (Q9JI51) Pfam (PF12352) | Rattus norvegicus (Norway rat) | Vesicle transport v-SNARE protein Vti1-like 2, Vti1-rp2 |
| 4 | D (D) | Syntaxin-6 | polymer | 82 | 9121.3 | 1 | UniProt (O43752) Pfam (PF05739) | Homo sapiens (human) | |
| 5 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence modifications
A: 48 - 118 (UniProt: O70480)
B: 184 - 251 (UniProt: O70319)
C: 115 - 192 (UniProt: Q9JI51)
D: 169 - 234 (UniProt: O43752)
| PDB | External Database | Details |
|---|---|---|
| Gly 45 | - | cloning artifact |
| Ser 46 | - | cloning artifact |
| Met 47 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 181 | - | cloning artifact |
| Ser 182 | - | cloning artifact |
| Met 183 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 112 | - | cloning artifact |
| Ser 113 | - | cloning artifact |
| Met 114 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 153 | - | cloning artifact |
| Ser 154 | - | cloning artifact |
| His 155 | - | cloning artifact |
| Met 156 | - | cloning artifact |
| Ala 157 | - | cloning artifact |
| Ser 158 | - | cloning artifact |
| Met 159 | - | cloning artifact |
| Thr 160 | - | cloning artifact |
| Gly 161 | - | cloning artifact |
| Gly 162 | - | cloning artifact |
| Asn 163 | - | cloning artifact |
| Asn 164 | - | cloning artifact |
| Met 165 | - | cloning artifact |
| Gly 166 | - | cloning artifact |
| Arg 167 | - | cloning artifact |
| Met 168 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 35507.1 | |
| All* | Total formula weight | 35507.1 |
