2NPQ

A Novel Lipid Binding Site in the p38 alpha MAP Kinase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Mitogen-activated protein kinase 14	polymer	367	42243.1	1	UniProt (Q16539) Pfam (PF00069)	Homo sapiens (human)	Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A
2	B, C (A)	octyl beta-D-glucopyranoside	non-polymer		292.4	2	Chemie (BOG)
3	D (A)	water	water		18.0	331	Chemie (HOH)

Sequence modifications

A: 2 - 360 (UniProt: Q16539)

PDB	External Database	Details
Met -6	-	expression tag
Ala -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42243.1
Non-Polymers*	Number of molecules	2
	Total formula weight	584.7
All*	Total formula weight	42827.9

*Water molecules are not included.