2NOV

Breakage-reunion domain of S.pneumoniae topo IV: crystal structure of a gram-positive quinolone target

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	DNA topoisomerase 4 subunit A	polymer	496	56455.4	4	UniProt (P72525) Pfam (PF00521) UniProt (by SIFTS) (Q3HYJ3) In PDB	Streptococcus pneumoniae	Topoisomerase IV subunit A
2		water	water		18.0	24	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 490 (UniProt: P72525)

PDB	External Database	Details
Thr 257	Ile 257	conflict
Leu 489	Ile 489	conflict
His 491	-	expression tag
His 492	-	expression tag
His 493	-	expression tag
His 494	-	expression tag
His 495	-	expression tag
His 496	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	225821.7
All*	Total formula weight	225821.7

*Water molecules are not included.