2NOF
Structure of Q315F human 8-oxoguanine glycosylase proximal crosslink to 8-oxoguanine DNA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3' | polymer | 15 | 4635.0 | 1 | |||
2 | C | 5'-D(*GP*CP*GP*TP*C*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3' | polymer | 15 | 4561.9 | 1 | |||
3 | A | N-glycosylase/DNA lyase | polymer | 325 | 36549.4 | 1 | UniProt (O15527) Pfam (PF07934) Pfam (PF00730) In PDB | Homo sapiens (human) | AP lyase |
4 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
5 | water | water | 18.0 | 192 | Chemie (HOH) |
Sequence modifications
A: 12 - 327 (UniProt: O15527)
PDB | External Database | Details |
---|---|---|
Ala 3 | - | cloning artifact |
Met 4 | - | cloning artifact |
Ala 5 | - | cloning artifact |
Asp 6 | - | cloning artifact |
Ile 7 | - | cloning artifact |
Gly 8 | - | cloning artifact |
Ser 9 | - | cloning artifact |
Glu 10 | - | cloning artifact |
Phe 11 | - | cloning artifact |
Cys 149 | Asn 149 | engineered mutation |
Phe 315 | Gln 315 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 45746.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 40.1 | |
All* | Total formula weight | 45786.5 |