2NO7
C4S dCK variant of dCK in complex with L-dC+ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | deoxycytidine kinase | polymer | 280 | 32659.6 | 2 | UniProt (P27707) Pfam (PF01712) | Homo sapiens (human) | dCK |
| 2 | C, E (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 3 | D, F (A, B) | 4-AMINO-1-(2-DEOXY-BETA-L-ERYTHRO-PENTOFURANOSYL)PYRIMIDIN-2(1H)-ONE | non-polymer | 227.2 | 2 | Chemie (LDC) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 260 (UniProt: P27707)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | cloning artifact |
| Gly -18 | - | cloning artifact |
| Ser -17 | - | cloning artifact |
| Ser -16 | - | cloning artifact |
| His -15 | - | cloning artifact |
| His -14 | - | cloning artifact |
| His -13 | - | cloning artifact |
| His -12 | - | cloning artifact |
| His -11 | - | cloning artifact |
| His -10 | - | cloning artifact |
| Ser -9 | - | cloning artifact |
| Ser -8 | - | cloning artifact |
| Gly -7 | - | cloning artifact |
| Leu -6 | - | cloning artifact |
| Val -5 | - | cloning artifact |
| Pro -4 | - | cloning artifact |
| Arg -3 | - | cloning artifact |
| Gly -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| His 0 | - | cloning artifact |
| Ser 9 | Cys 9 | engineered mutation |
| Ser 45 | Cys 45 | engineered mutation |
| Ser 59 | Cys 59 | engineered mutation |
| Ser 146 | Cys 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65319.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1308.8 | |
| All* | Total formula weight | 66628.0 |
