2NO7
C4S dCK variant of dCK in complex with L-dC+ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | deoxycytidine kinase | polymer | 280 | 32659.6 | 2 | UniProt (P27707) Pfam (PF01712) | Homo sapiens (human) | dCK |
| 2 | C, E (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 3 | D, F (A, B) | 4-AMINO-1-(2-DEOXY-BETA-L-ERYTHRO-PENTOFURANOSYL)PYRIMIDIN-2(1H)-ONE | non-polymer | 227.2 | 2 | Chemie (LDC) PubChem (18528811) PubChem (637) PubChem (13711) PubChem (159354) PubChem (23725055) PubChem (44322004) PubChem (44721303) PubChem (451823) PubChem (453557) PubChem (688446) PubChem (1223201) PubChem (57514101) PubChem (58597108) PubChem (59949021) PubChem (70971940) PubChem (6560425) PubChem (12800110) PubChem (6419441) PubChem (6541396) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 260 (UniProt: P27707)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | cloning artifact |
| Gly -18 | - | cloning artifact |
| Ser -17 | - | cloning artifact |
| Ser -16 | - | cloning artifact |
| His -15 | - | cloning artifact |
| His -14 | - | cloning artifact |
| His -13 | - | cloning artifact |
| His -12 | - | cloning artifact |
| His -11 | - | cloning artifact |
| His -10 | - | cloning artifact |
| Ser -9 | - | cloning artifact |
| Ser -8 | - | cloning artifact |
| Gly -7 | - | cloning artifact |
| Leu -6 | - | cloning artifact |
| Val -5 | - | cloning artifact |
| Pro -4 | - | cloning artifact |
| Arg -3 | - | cloning artifact |
| Gly -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| His 0 | - | cloning artifact |
| Ser 9 | Cys 9 | engineered mutation |
| Ser 45 | Cys 45 | engineered mutation |
| Ser 59 | Cys 59 | engineered mutation |
| Ser 146 | Cys 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65319.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1308.8 | |
| All* | Total formula weight | 66628.0 |
