2NNY

Crystal structure of the Ets1 dimer DNA complex.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (C)	5'-D(*T*AP*GP*AP*CP*AP*GP*GP*AP*AP*GP*CP*AP*CP*TP*TP*CP*CP*TP*GP*GP*AP*G)-3'	polymer	23	7114.6	1
2	B (D)	5'-D(*A*CP*TP*CP*CP*AP*GP*GP*AP*AP*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*TP*CP*T)-3'	polymer	23	7007.5	1
3	C, D (A, B)	C-ets-1 protein	polymer	171	19878.5	2	UniProt (P14921) Pfam (PF00178)	Homo sapiens (human)	p54
4	E, F, G, H (C, D, A, B)	water	water		18.0	46	Chemie (HOH)

Sequence modifications

A, B: 280 - 441 (UniProt: P14921)

PDB	External Database	Details
Met 271	-	expression tag
Lys 272	-	expression tag
His 273	-	expression tag
His 274	-	expression tag
His 275	-	expression tag
His 276	-	expression tag
His 277	-	expression tag
Pro 278	-	expression tag
Met 279	-	expression tag
Ser 350	Cys 350	engineered mutation
Ser 416	Cys 416	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	53879.1
All*	Total formula weight	53879.1

*Water molecules are not included.