2NNA

Structure of the MHC class II molecule HLA-DQ8 bound with a deamidated gluten peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	MHC class II antigen	polymer	184	21047.5	1	UniProt (Q5Y7F5) Pfam (PF00993) Pfam (PF07654) UniProt (by SIFTS) (P01909)	Homo sapiens (human)
2	B (B)	MHC class II antigen	polymer	207	23779.6	1	UniProt (Q5Y7F6) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01920)	Homo sapiens (human)
3	C (C)	gluten peptide	polymer	18	2008.0	1	UniProt (P18573)
4	D, E, F (A, B, C)	water	water		18.0	311	Chemie (HOH)

Sequence modifications

B: 1 - 192 (UniProt: Q5Y7F6)

PDB	External Database	Details
Gly -14	-	expression tag
Gly -13	-	expression tag
Gly -12	-	expression tag
Gly -11	-	expression tag
Ser -10	-	expression tag
Ile -9	-	expression tag
Glu -8	-	expression tag
Gly -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

C: -3 - 14 (UniProt: P18573)

PDB	External Database	Details
Glu 3	Gln 249	conflict
Glu 11	Gln 257	conflict

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	46835.0
All*	Total formula weight	46835.0

*Water molecules are not included.