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2NL9

Crystal structure of the Mcl-1:Bim BH3 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
FUSION PROTEIN CONSISTING OF Induced myeloid leukemia cell differentiation protein Mcl-1 homologpolymer15717909.91UniProt (P97287)
UniProt (Q07820)
Pfam (PF00452)
Mus musculus (Mouse)
2B
(B)
Bcl-2-like protein 11polymer263274.71UniProt (O43521)
Pfam (PF08945)
Homo sapiens (human)Bcl2-interacting mediator of cell death
3C, D, E, F, G...
(A, B)
ZINC IONnon-polymer65.47Chemie (ZN)
4I
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5K, L
(A, B)
waterwater18.0201Chemie (HOH)
Sequence modifications
A: 171 - 208 (UniProt: P97287)
A: 209 - 327 (UniProt: Q07820)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight21184.6
Non-Polymers*Number of molecules8
Total formula weight493.3
All*Total formula weight21677.9
*Water molecules are not included.

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PDB entries from 2025-10-29

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