2NGR
TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | PROTEIN (GTP BINDING PROTEIN (G25K)) | polymer | 191 | 21283.6 | 1 | UniProt (P60953) Pfam (PF00071) In PDB | Homo sapiens (human) | CDC42/CDC42GAP |
2 | B | PROTEIN (GTPASE ACTIVATING PROTEIN (RHG)) | polymer | 234 | 26451.3 | 1 | UniProt (Q07960) Pfam (PF00620) In PDB | Homo sapiens (human) | CDC42/CDC42GAP |
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
5 | A | ALUMINUM FLUORIDE | non-polymer | 84.0 | 1 | Chemie (AF3) | |||
6 | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
B: 229 - 462 (UniProt: Q07960)
PDB | External Database | Details |
---|---|---|
Ala 305 | Arg 282 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 47734.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 551.5 | |
All* | Total formula weight | 48286.3 |