2NGR
TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN (GTP BINDING PROTEIN (G25K)) | polymer | 191 | 21283.6 | 1 | UniProt (P60953) Pfam (PF00071) | Homo sapiens (human) | CDC42/CDC42GAP |
| 2 | B (B) | PROTEIN (GTPASE ACTIVATING PROTEIN (RHG)) | polymer | 234 | 26451.3 | 1 | UniProt (Q07960) Pfam (PF00620) | Homo sapiens (human) | CDC42/CDC42GAP |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 5 | E (A) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 1 | Chemie (AF3) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
B: 229 - 462 (UniProt: Q07960)
| PDB | External Database | Details |
|---|---|---|
| Ala 305 | Arg 282 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47734.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 551.5 | |
| All* | Total formula weight | 48286.3 |
