2NGR
TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN (GTP BINDING PROTEIN (G25K)) | polymer | 191 | 21283.6 | 1 | UniProt (P60953) Pfam (PF00071) | Homo sapiens (human) | CDC42/CDC42GAP |
| 2 | B (B) | PROTEIN (GTPASE ACTIVATING PROTEIN (RHG)) | polymer | 234 | 26451.3 | 1 | UniProt (Q07960) Pfam (PF00620) | Homo sapiens (human) | CDC42/CDC42GAP |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 5 | E (A) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 1 | Chemie (AF3) PubChem (2124) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
B: 229 - 462 (UniProt: Q07960)
| PDB | External Database | Details |
|---|---|---|
| Ala 305 | Arg 282 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47734.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 551.5 | |
| All* | Total formula weight | 48286.3 |
