2N9Y
Structure of the Integrin alphaIIb-beta3(A711P) Transmembrane Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin alpha-IIb | polymer | 42 | 4783.9 | 1 | UniProt (P08514) Pfam (PF00357) | Homo sapiens (human) | GPalpha IIb, GPIIb, Platelet membrane glycoprotein IIb, Integrin alpha-IIb heavy chain, Integrin alpha-IIb light chain, form 1, Integrin alpha-IIb light chain, form 2 |
| 2 | B (B) | Integrin beta-3 | polymer | 43 | 4744.9 | 1 | UniProt (P05106) | Homo sapiens (human) | Platelet membrane glycoprotein IIIa, GPIIIa |
Sequence modifications
A: 958 - 998 (UniProt: P08514)
B: 686 - 727 (UniProt: P05106)
| PDB | External Database | Details |
|---|---|---|
| Gly 957 | - | expression tag |
| Cys 963 | Ala 994 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 685 | - | expression tag |
| Ser 687 | Cys 713 | engineered mutation |
| Cys 690 | Gly 716 | engineered mutation |
| Pro 711 | Ala 737 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 9528.8 | |
| All* | Total formula weight | 9528.8 |
