2N7L
NMR structure of the N-domain of troponin C bound to the switch region of troponin I and the covalent levosimendan analog i9
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C | Troponin C/Troponin I chimera | polymer | 141 | 16218.3 | 1 | UniProt (P63316) UniProt (P19429) Pfam (PF13833) In PDB | Homo sapiens (human) | TN-C, Cardiac troponin I |
2 | C | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
C: 1 - 89 (UniProt: P63316)
C: 97 - 126 (UniProt: P19429)
PDB | External Database | Details |
---|---|---|
Met -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
Gly -7 | - | expression tag |
Gly -6 | - | expression tag |
Leu -5 | - | expression tag |
Val -4 | - | expression tag |
Pro -3 | - | expression tag |
Arg -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Ser 35 | Cys 35 | engineered mutation |
Glu 90 | - | linker |
Asn 91 | - | linker |
Leu 92 | - | linker |
Tyr 93 | - | linker |
Phe 94 | - | linker |
Gln 95 | - | linker |
Gly 96 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 16218.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 40.1 | |
All* | Total formula weight | 16258.4 |