2N4Q

Solution NMR structure of CBX8 in complex with AF9 (CBX8-AF9)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Chromobox protein homolog 8	polymer	24	2577.9	1	UniProt (Q9HC52) In PDB	Homo sapiens (human)	Polycomb 3 homolog, Pc3, hPc3, Rectachrome 1
2	B	Protein AF-9	polymer	70	8278.4	1	UniProt (P42568) Pfam (PF17793) In PDB	Homo sapiens (human)	ALL1-fused gene from chromosome 9 protein, Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein, YEATS domain-containing protein 3

Sequence modifications

A: 327 - 349 (UniProt: Q9HC52)

PDB	External Database	Details
Thr 326	-	expression tag

B: 500 - 568 (UniProt: P42568)

PDB	External Database	Details
Met 499	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	10856.3
All*	Total formula weight	10856.3

*Water molecules are not included.