2N1T
Dynamic binding mode of a synaptotagmin-1-SNARE complex in solution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Vesicle-associated membrane protein 2 | polymer | 69 | 8045.0 | 1 | UniProt (P63045) Pfam (PF00957) In PDB | Rattus norvegicus (brown rat rat rats) | VAMP-2, Synaptobrevin-2 |
| 2 | B | Syntaxin-1A | polymer | 72 | 8429.5 | 1 | UniProt (P32851) Pfam (PF05739) In PDB | Rattus norvegicus (brown rat rat rats) | Neuron-specific antigen HPC-1, Synaptotagmin-associated 35 kDa protein, P35A |
| 3 | C | Synaptosomal-associated protein 25 | polymer | 77 | 9030.1 | 1 | UniProt (P60880) In PDB | Homo sapiens (human) | SNAP-25, SNAP-25A, Super protein, SUP, Synaptosomal-associated 25 kDa protein |
| 4 | D | Synaptosomal-associated protein 25 | polymer | 74 | 8458.4 | 1 | UniProt (P60880) In PDB | Homo sapiens (human) | SNAP-25, SNAP-25A, Super protein, SUP, Synaptosomal-associated 25 kDa protein |
| 5 | E | Synaptotagmin-1 | polymer | 156 | 17465.2 | 1 | UniProt (P21579) Pfam (PF00168) In PDB | Homo sapiens (human) | Synaptotagmin I, SytI, p65 |
Sequence modifications
E: 271 - 418 (UniProt: P21579)
| PDB | External Database | Details |
|---|---|---|
| Ser 263 | - | expression tag |
| Gly 264 | - | expression tag |
| Gly 265 | - | expression tag |
| Gly 266 | - | expression tag |
| Gly 267 | - | expression tag |
| Gly 268 | - | expression tag |
| Ile 269 | - | expression tag |
| Leu 270 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 51428.3 | |
| All* | Total formula weight | 51428.3 |
