2MZD
Characterization of the p300 Taz2-p53 TAD2 Complex and Comparison with the p300 Taz2-p53 TAD1 Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Histone acetyltransferase p300 | polymer | 90 | 9963.8 | 1 | UniProt (Q09472) Pfam (PF02135) In PDB | Homo sapiens (human) | p300 HAT, E1A-associated protein p300 |
| 2 | B | Cellular tumor antigen p53 | polymer | 25 | 2851.1 | 1 | UniProt (P04637) Pfam (PF18521) In PDB | Homo sapiens (human) | Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53 |
Sequence modifications
A: 1 - 90 (UniProt: Q09472)
| PDB | External Database | Details |
|---|---|---|
| Ala 16 | Cys 1738 | engineered mutation |
| Ala 24 | Cys 1746 | engineered mutation |
| Ala 67 | Cys 1789 | engineered mutation |
| Ala 68 | Cys 1790 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 12814.9 | |
| All* | Total formula weight | 12814.9 |
