2MV7
Solution NMR structure of DOT1L in complex with AF9 (DOT1L-AF9)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Protein AF-9 | polymer | 69 | 8147.2 | 1 | UniProt (P42568) Pfam (PF17793) In PDB | Homo sapiens (human) | ALL1-fused gene from chromosome 9 protein, Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein, YEATS domain-containing protein 3 |
| 2 | B | Histone-lysine N-methyltransferase, H3 lysine-79 specific | polymer | 25 | 2667.1 | 1 | UniProt (Q8TEK3) In PDB | Homo sapiens (human) | DOT1-like protein, Histone H3-K79 methyltransferase, H3-K79-HMTase, Lysine N-methyltransferase 4 |
Sequence modifications
B: 877 - 900 (UniProt: Q8TEK3)
| PDB | External Database | Details |
|---|---|---|
| Thr 876 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 10814.3 | |
| All* | Total formula weight | 10814.3 |
