2MLS
Membrane Bilayer complex with Matrix Metalloproteinase-12 at its Beta-face
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Macrophage metalloelastase | polymer | 164 | 18177.4 | 1 | UniProt (P39900) Pfam (PF00413) In PDB | Homo sapiens (human) | MME, Macrophage elastase, ME, hME, Matrix metalloproteinase-12, MMP-12 |
| 2 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 4 | A | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 678.9 | 125 | Chemie (PX4) |
Sequence modifications
A: 100 - 263 (UniProt: P39900)
| PDB | External Database | Details |
|---|---|---|
| Ala 219 | Glu 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18177.4 | |
| Non-Polymers* | Number of molecules | 130 |
| Total formula weight | 85118.6 | |
| All* | Total formula weight | 103295.9 |
