2MFQ
NMR solution structures of FRS2a PTB domain with neurotrophin receptor TrkB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Fibroblast growth factor receptor substrate 2 | polymer | 115 | 13441.0 | 1 | UniProt (Q8WU20) Pfam (PF02174) In PDB | Homo sapiens (human) | FGFR substrate 2, FGFR-signaling adaptor SNT, Suc1-associated neurotrophic factor target 1, SNT-1 |
| 2 | B | BDNF/NT-3 growth factors receptor | polymer | 23 | 2553.9 | 1 | UniProt (Q16620) In PDB | Homo sapiens | GP145-TrkB, Trk-B, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Tropomyosin-related kinase B |
Sequence modifications
A: 11 - 122 (UniProt: Q8WU20)
| PDB | External Database | Details |
|---|---|---|
| Ser 8 | - | EXPRESSION TAG |
| His 9 | - | EXPRESSION TAG |
| Met 10 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 15994.9 | |
| All* | Total formula weight | 15994.9 |
