2MAW

NMR structures of the alpha7 nAChR transmembrane domain.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Neuronal acetylcholine receptor subunit alpha-7	polymer	137	14582.0	1	UniProt (P36544) Pfam (PF02932)	Homo sapiens (human)	CHRNA7-DR1, D-10

Sequence modifications

A: 4 - 102 (UniProt: P36544)

PDB	External Database	Details
Ser 1	-	expression tag
Asn 2	-	expression tag
Ala 3	-	expression tag
Glu 4	Arg 228	engineered mutation
Glu 5	Arg 229	engineered mutation
Glu 6	Thr 230	engineered mutation
Ser 61	Ala 285	engineered mutation
Ser 66	Val 290	engineered mutation
Ser 68	Leu 292	engineered mutation
Glu 102	Lys 326	engineered mutation

A: 108 - 137 (UniProt: P36544)

PDB	External Database	Details
Gly 103	-	linker
Gly 104	-	linker
Gly 105	-	linker
Glu 106	-	linker
Gly 107	-	linker
Ile 108	Val 467	engineered mutation
Glu 137	Ala 496	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	14582.0
All*	Total formula weight	14582.0

*Water molecules are not included.