2MAK
Solution structure of the STIM1 CC1-CC2 homodimer in complex with two Orai1 C-terminal domains.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Stromal interaction molecule 1 | polymer | 82 | 9703.0 | 2 | UniProt (Q13586) Pfam (PF16533) | Homo sapiens (human) | |
| 2 | B, D (B, D) | Calcium release-activated calcium channel protein 1 | polymer | 23 | 2654.8 | 2 | UniProt (Q96D31) | Homo sapiens (human) | Protein orai-1, Transmembrane protein 142A |
Sequence modifications
A, C: 312 - 387 (UniProt: Q13586)
B, D: 272 - 292 (UniProt: Q96D31)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
| His -3 | - | expression tag |
| Met -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 24715.6 | |
| All* | Total formula weight | 24715.6 |
