2MAK
Solution structure of the STIM1 CC1-CC2 homodimer in complex with two Orai1 C-terminal domains.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Stromal interaction molecule 1 | polymer | 82 | 9703.0 | 2 | UniProt (Q13586) Pfam (PF16533) In PDB | Homo sapiens (human) | |
2 | B, D | Calcium release-activated calcium channel protein 1 | polymer | 23 | 2654.8 | 2 | UniProt (Q96D31) In PDB | Homo sapiens (human) | Protein orai-1, Transmembrane protein 142A |
Sequence modifications
A, C: 312 - 387 (UniProt: Q13586)
B, D: 272 - 292 (UniProt: Q96D31)
PDB | External Database | Details |
---|---|---|
Gly -5 | - | expression tag |
Ser -4 | - | expression tag |
His -3 | - | expression tag |
Met -2 | - | expression tag |
Ala -1 | - | expression tag |
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 24715.6 | |
All* | Total formula weight | 24715.6 |