2M2F

The membran-proximal domain of ADAM17

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Disintegrin and metalloproteinase domain-containing protein 17	polymer	88	9905.1	1	UniProt (P78536) Pfam (PF16698) In PDB	Homo sapiens (human)	ADAM 17, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme

Sequence modifications

A: 1 - 62 (UniProt: P78536)

PDB	External Database	Details
Met -25	-	expression tag
Gly -24	-	expression tag
Ser -23	-	expression tag
Ser -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Leu -12	-	expression tag
Val -11	-	expression tag
Pro -10	-	expression tag
Arg -9	-	expression tag
Gly -8	-	expression tag
Ser -7	-	expression tag
His -6	-	expression tag
Met -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	9905.1
All*	Total formula weight	9905.1

*Water molecules are not included.