2M20
EGFR transmembrane - juxtamembrane (TM-JM) segment in bicelles: MD guided NMR refined structure.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Epidermal growth factor receptor | polymer | 60 | 6779.3 | 2 | UniProt (P00533) Pfam (PF21314) | Homo sapiens (human) | Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 |
Sequence modifications
A, B: 1 - 56 (UniProt: P00533)
| PDB | External Database | Details |
|---|---|---|
| Leu 9 | Met 650 | engineered mutation |
| Ile 27 | Met 668 | engineered mutation |
| Lys 57 | - | expression tag |
| Leu 58 | - | expression tag |
| Trp 59 | - | expression tag |
| Ser 60 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 13558.5 | |
| All* | Total formula weight | 13558.5 |
