2M1X

TICAM-1 TIR domain structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	TIR domain-containing adapter molecule 1	polymer	168	19132.7	1	UniProt (Q8IUC6) In PDB	Homo sapiens (human)	TICAM-1, Proline-rich, vinculin and TIR domain-containing protein B, Putative NF-kappa-B-activating protein 502H, Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta, TIR domain-containing adapter protein inducing IFN-beta

Sequence modifications

A: 387 - 545 (UniProt: Q8IUC6)

PDB	External Database	Details
Met 386	-	expression tag
His 434	Pro 434	engineered mutation
Leu 546	-	expression tag
Glu 547	-	expression tag
His 548	-	expression tag
His 549	-	expression tag
His 550	-	expression tag
His 551	-	expression tag
His 552	-	expression tag
His 553	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	19132.7
All*	Total formula weight	19132.7

*Water molecules are not included.