2M0Z
cis form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 13 | polymer | 97 | 10067.4 | 1 | UniProt (Q12923) Pfam (PF00595) | Homo sapiens (human) | Fas-associated protein-tyrosine phosphatase 1, FAP-1, PTP-BAS, Protein-tyrosine phosphatase 1E, PTP-E1, hPTPE1, Protein-tyrosine phosphatase PTPL1 |
| 2 | B (A) | 3,3'-(E)-diazene-1,2-diylbis{6-[(chloroacetyl)amino]benzenesulfonic acid} | non-polymer | 525.3 | 1 | Chemie (33B) |
Sequence modifications
A: 2 - 97 (UniProt: Q12923)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Cys 22 | Ser 1381 | engineered mutation |
| Cys 77 | Glu 1436 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10067.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 525.3 | |
| All* | Total formula weight | 10592.7 |
