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2M0V

Complex structure of C-terminal CFTR peptide and extended PDZ2 domain from NHERF1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1polymer12814101.01UniProt (O14745)
Pfam (PF00595)
Homo sapiens (human)NHERF-1, Ezrin-radixin-moesin-binding phosphoprotein 50, EBP50, Regulatory cofactor of Na(+)/H(+) exchanger, Sodium-hydrogen exchanger regulatory factor 1, Solute carrier family 9 isoform A3 regulatory factor 1
2B
(B)
C-terminal CFTR peptidepolymer5632.71
Sequence modifications
A: 150 - 270 (UniProt: O14745)
PDBExternal DatabaseDetails
Gly 143-expression tag
Ile 144-expression tag
Asp 145-expression tag
Pro 146-expression tag
Phe 147-expression tag
Thr 148-expression tag
Met 149-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight14733.7
All*Total formula weight14733.7
*Water molecules are not included.

239803

PDB entries from 2025-08-06

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