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2M0U

Complex structure of C-terminal CFTR peptide and extended PDZ1 domain from NHERF1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ANa(+)/H(+) exchange regulatory cofactor NHE-RF1polymer11712822.61UniProt (O14745)
Pfam (PF00595)
In PDB
Homo sapiens (human)NHERF-1, Ezrin-radixin-moesin-binding phosphoprotein 50, EBP50, Regulatory cofactor of Na(+)/H(+) exchanger, Sodium-hydrogen exchanger regulatory factor 1, Solute carrier family 9 isoform A3 regulatory factor 1
2BC-terminal CFTR peptidepolymer5632.71
Sequence modifications
A: 11 - 120 (UniProt: O14745)
PDBExternal DatabaseDetails
Gly 4-expression tag
Ile 5-expression tag
Asp 6-expression tag
Pro 7-expression tag
Phe 8-expression tag
Thr 9-expression tag
Met 10-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight13455.3
All*Total formula weight13455.3
*Water molecules are not included.

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PDB entries from 2024-04-24

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