2M03

Solution structure of BCL-xL determined with selective isotope labelling of I,L,V sidechains

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Bcl-2-like protein 1	polymer	181	20804.9	1	UniProt (Q07817) Pfam (PF02180) Pfam (PF00452)	Homo sapiens (human)	Bcl2-L-1, Apoptosis regulator Bcl-X

Sequence modifications

A: 5 - 173 (UniProt: Q07817)

PDB	External Database	Details
Met 1	-	expression tag
Ser 2	-	expression tag
Met 3	-	expression tag
Ala 4	-	expression tag
-	Met 45	deletion
-	Glu 46	deletion
-	Thr 47	deletion
-	Pro 48	deletion
-	Ser 49	deletion
-	Ala 50	deletion
-	Ile 51	deletion
-	Asn 52	deletion
-	Gly 53	deletion
-	Asn 54	deletion
-	Pro 55	deletion
-	Ser 56	deletion
-	Trp 57	deletion
-	His 58	deletion
-	Leu 59	deletion
-	Ala 60	deletion
-	Asp 61	deletion
-	Ser 62	deletion
-	Pro 63	deletion
-	Ala 64	deletion
-	Val 65	deletion
-	Asn 66	deletion
-	Gly 67	deletion
-	Ala 68	deletion
-	Thr 69	deletion
-	Gly 70	deletion
-	His 71	deletion
-	Ser 72	deletion
-	Ser 73	deletion
-	Ser 74	deletion
-	Leu 75	deletion
-	Asp 76	deletion
-	Ala 77	deletion
-	Arg 78	deletion
-	Glu 79	deletion
-	Val 80	deletion
-	Ile 81	deletion
-	Pro 82	deletion
-	Met 83	deletion
-	Ala 84	deletion
Leu 174	-	expression tag
Glu 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag
His 178	-	expression tag
His 179	-	expression tag
His 180	-	expression tag
His 181	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	20804.9
All*	Total formula weight	20804.9

*Water molecules are not included.