2LOB

PDZ Domain of CAL (Cystic Fibrosis Transmembrane Regulator-Associated Ligand)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Golgi-associated PDZ and coiled-coil motif-containing protein	polymer	112	12528.1	1	UniProt (Q9HD26) Pfam (PF00595) In PDB	Homo sapiens (human)	CFTR-associated ligand, Fused in glioblastoma, PDZ protein interacting specifically with TC10, PIST
2	B	Cystic fibrosis transmembrane conductance regulator	polymer	8	990.0	1	UniProt (P13569) In PDB	Homo sapiens	CFTR, ATP-binding cassette sub-family C member 7, Channel conductance-controlling ATPase, cAMP-dependent chloride channel

Sequence modifications

A: 28 - 112 (UniProt: Q9HD26)

PDB	External Database	Details
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
His 14	-	expression tag
Ile 15	-	expression tag
Glu 16	-	expression tag
Gly 17	-	expression tag
Arg 18	-	expression tag
His 19	-	expression tag
Met 20	-	expression tag
Glu 21	-	expression tag
Asn 22	-	expression tag
Leu 23	-	expression tag
Tyr 24	-	expression tag
Phe 25	-	expression tag
Gln 26	-	expression tag
Gly 27	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	13518.2
All*	Total formula weight	13518.2

*Water molecules are not included.