2LO4

NMR Solution Structure of Optineurin Zinc-finger Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Optineurin	polymer	51	5567.4	1	UniProt (Q96CV9) Pfam (PF18414)	Homo sapiens (human)	E3-14.7K-interacting protein, FIP-2, Huntingtin yeast partner L, Huntingtin-interacting protein 7, HIP-7, Huntingtin-interacting protein L, NEMO-related protein, Optic neuropathy-inducing protein, Transcription factor IIIA-interacting protein, TFIIIA-IntP
2	B (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

A: 24 - 51 (UniProt: Q96CV9)

PDB	External Database	Details
Met 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Leu 14	-	expression tag
Val 15	-	expression tag
Pro 16	-	expression tag
Arg 17	-	expression tag
Gly 18	-	expression tag
Ser 19	-	expression tag
His 20	-	expression tag
Met 21	-	expression tag
Ala 22	-	expression tag
Ser 23	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	5567.4
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	5632.8

*Water molecules are not included.