2LFE

Solution NMR structure of N-terminal domain of human E3 ubiquitin-protein ligase HECW2, Northeast structural genomics consortium (NESG) target ht6306A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	E3 ubiquitin-protein ligase HECW2	polymer	138	15947.8	1	UniProt (Q9P2P5) Pfam (PF16562) In PDB	Homo sapiens (human)	HECT, C2 and WW domain-containing protein 2, NEDD4-like E3 ubiquitin-protein ligase 2

Sequence modifications

A: 43 - 162 (UniProt: Q9P2P5)

PDB	External Database	Details
Met 25	-	expression tag
His 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
His 29	-	expression tag
His 30	-	expression tag
His 31	-	expression tag
Ser 32	-	expression tag
Ser 33	-	expression tag
Gln 34	-	expression tag
Arg 35	-	expression tag
Glu 36	-	expression tag
Asn 37	-	expression tag
Leu 38	-	expression tag
Tyr 39	-	expression tag
Phe 40	-	expression tag
Gln 41	-	expression tag
Gly 42	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	15947.8
All*	Total formula weight	15947.8

*Water molecules are not included.