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2LB1

Structure of the second domain of human Smurf1 in complex with a human Smad1 derived peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase SMURF1polymer364170.61UniProt (Q9HCE7)
Pfam (PF00397)
Homo sapiens (human)hSMURF1, SMAD ubiquitination regulatory factor 1, SMAD-specific E3 ubiquitin-protein ligase 1
2B
(B)
Mothers against decapentaplegic homolog 1polymer151477.61UniProt (Q15797)Homo sapiensMAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1, SMAD 1, Smad1, hSMAD1, Transforming growth factor-beta-signaling protein 1, BSP-1
Sequence modifications
B: 220 - 233 (UniProt: Q15797)
PDBExternal DatabaseDetails
Nh2 234-insertion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight5648.2
All*Total formula weight5648.2
*Water molecules are not included.

238582

PDB entries from 2025-07-09

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