2LB0
Structure of the first WW domain of human Smurf1 in complex with a di-phosphorylated human Smad1 derived peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | E3 ubiquitin-protein ligase SMURF1 | polymer | 36 | 4137.5 | 1 | UniProt (Q9HCE7) Pfam (PF00397) In PDB | Homo sapiens (human) | hSMURF1, SMAD ubiquitination regulatory factor 1, SMAD-specific E3 ubiquitin-protein ligase 1 |
| 2 | B | Mothers against decapentaplegic homolog 1 | polymer | 10 | 1182.0 | 1 | UniProt (Q15797) In PDB | Homo sapiens | MAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1, SMAD 1, Smad1, hSMAD1, Transforming growth factor-beta-signaling protein 1, BSP-1 |
Sequence modifications
A: 235 - 267 (UniProt: Q9HCE7)
| PDB | External Database | Details |
|---|---|---|
| Gly 232 | - | EXPRESSION TAG |
| Ala 233 | - | EXPRESSION TAG |
| Met 234 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 5319.5 | |
| All* | Total formula weight | 5319.5 |
