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2LAX

Structure of first WW domain of human YAP in complex with a human Smad1 doubly-phosphorilated derived peptide.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Yorkie homologpolymer404540.01UniProt (P46937)
Pfam (PF00397)
Homo sapiens (human)65 kDa Yes-associated protein, YAP65
2B
(B)
Mothers against decapentaplegic homolog 1polymer91137.01UniProt (Q15797)Homo sapiensMAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1, SMAD 1, Smad1, hSMAD1, Transforming growth factor-beta-signaling protein 1, BSP-1
Sequence modifications
A: 170 - 205 (UniProt: P46937)
PDBExternal DatabaseDetails
Gly 166-expression tag
Ala 167-expression tag
Met 168-expression tag
Glu 169-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight5677.0
All*Total formula weight5677.0
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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