2L23

NMR structure of the ACID (ACtivator Interacting Domain) of the human mediator Med25 protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Mediator of RNA polymerase II transcription subunit 25	polymer	167	19220.3	1	UniProt (Q71SY5) Pfam (PF11232) In PDB	Homo sapiens (human)	Mediator complex subunit 25, Activator-recruited cofactor 92 kDa component, ARC92, Activator interaction domain-containing protein 1, p78

Sequence modifications

A: 2 - 159 (UniProt: Q71SY5)

PDB	External Database	Details
Met 1	-	initiating methionine
Leu 160	-	expression tag
Glu 161	-	expression tag
His 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	19220.3
All*	Total formula weight	19220.3

*Water molecules are not included.