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2L23

NMR structure of the ACID (ACtivator Interacting Domain) of the human mediator Med25 protein

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mediator of RNA polymerase II transcription subunit 25polymer16719220.31UniProt (Q71SY5)
Pfam (PF11232)
Homo sapiens (human)Mediator complex subunit 25, Activator-recruited cofactor 92 kDa component, ARC92, Activator interaction domain-containing protein 1, p78
Sequence modifications
A: 2 - 159 (UniProt: Q71SY5)
PDBExternal DatabaseDetails
Met 1-initiating methionine
Leu 160-expression tag
Glu 161-expression tag
His 162-expression tag
His 163-expression tag
His 164-expression tag
His 165-expression tag
His 166-expression tag
His 167-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19220.3
All*Total formula weight19220.3
*Water molecules are not included.

237423

PDB entries from 2025-06-11

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