2KSO

EphA2:SHIP2 SAM:SAM complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Ephrin type-A receptor 2	polymer	82	9401.8	1	UniProt (P29317) Pfam (PF00536)	Homo sapiens (human)	Tyrosine-protein kinase receptor ECK, Epithelial cell kinase
2	B (B)	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2	polymer	76	8671.6	1	UniProt (O15357) Pfam (PF00536)	Homo sapiens (human)	SH2 domain-containing inositol-5'-phosphatase 2, SHIP-2, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, Protein 51C

Sequence modifications

A: 14 - 78 (UniProt: P29317)

PDB	External Database	Details
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
Gly 5	-	expression tag
Leu 6	-	expression tag
Val 7	-	expression tag
Pro 8	-	expression tag
Arg 9	-	expression tag
Gly 10	-	expression tag
Ser 11	-	expression tag
His 12	-	expression tag
Met 13	-	expression tag

B: 28 - 86 (UniProt: O15357)

PDB	External Database	Details
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
Ser 17	-	expression tag
Ser 18	-	expression tag
Gly 19	-	expression tag
Leu 20	-	expression tag
Val 21	-	expression tag
Pro 22	-	expression tag
Arg 23	-	expression tag
Gly 24	-	expression tag
Ser 25	-	expression tag
His 26	-	expression tag
Met 27	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	18073.4
All*	Total formula weight	18073.4

*Water molecules are not included.