2KKF
Solution structure of MLL CXXC domain in complex with palindromic CPG DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase HRX | polymer | 59 | 6678.0 | 1 | UniProt (Q03164) Pfam (PF02008) | Homo sapiens (human) | Zinc finger protein HRX, ALL-1, Trithorax-like protein, Lysine N-methyltransferase 2A, CXXC-type zinc finger protein 7 |
| 2 | B, C (B, C) | 5'-D(*CP*CP*CP*TP*GP*CP*GP*CP*AP*GP*GP*G)-3' | polymer | 12 | 3664.4 | 2 | |||
| 3 | D, E (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A: 1147 - 1203 (UniProt: Q03164)
| PDB | External Database | Details |
|---|---|---|
| Gly 1145 | - | expression tag |
| Ser 1146 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 14006.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 14137.6 |
