2K91
Enhancing the activity of insulin by stereospecific unfolding
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Insulin | polymer | 21 | 2383.7 | 1 | UniProt (P01308) | Homo sapiens | Insulin B chain, Insulin A chain |
| 2 | B (B) | Insulin | polymer | 30 | 3334.8 | 1 | UniProt (P01308) Pfam (PF00049) | Homo sapiens | Insulin B chain, Insulin A chain |
Sequence modifications
B: 1 - 30 (UniProt: P01308)
| PDB | External Database | Details |
|---|---|---|
| Asp 10 | His 34 | engineered mutation |
| Ala 24 | Phe 48 | engineered mutation |
| Lys 28 | Pro 52 | engineered mutation |
| Pro 29 | Lys 53 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 5718.5 | |
| All* | Total formula weight | 5718.5 |
