2K7A
Ensemble Structures of the binary complex between the SH3 and SH2 domain of interleukin-2 tyrosine kinase.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SH3 domain of Tyrosine-protein kinase ITK/TSK | polymer | 63 | 7355.9 | 1 | UniProt (Q03526) Pfam (PF00018) | Mus musculus (mouse) | T-cell-specific kinase, IL-2-inducible T-cell kinase, Kinase EMT, Kinase TLK |
| 2 | B (B) | SH2 domain of Tyrosine-protein kinase ITK/TSK | polymer | 110 | 12678.3 | 1 | UniProt (Q03526) Pfam (PF00017) | Mus musculus (mouse) | T-cell-specific kinase, IL-2-inducible T-cell kinase, Kinase EMT, Kinase TLK |
Sequence modifications
A: 171 - 231 (UniProt: Q03526)
B: 232 - 338 (UniProt: Q03526)
| PDB | External Database | Details |
|---|---|---|
| Gly 169 | - | expression tag |
| Ser 170 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 230 | - | expression tag |
| Ser 231 | - | expression tag |
| Gly 339 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20034.3 | |
| All* | Total formula weight | 20034.3 |
