2K2G
Solution structure of the wild-type catalytic domain of human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Macrophage metalloelastase | polymer | 165 | 18366.6 | 1 | UniProt (P39900) Pfam (PF00413) In PDB | Homo sapiens (Human) | HME, Matrix metalloproteinase-12, MMP-12, Macrophage elastase, ME |
| 2 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A | N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine | non-polymer | 363.5 | 1 | Chemie (DSV) |
Sequence modifications
A: 100 - 263 (UniProt: P39900)
| PDB | External Database | Details |
|---|---|---|
| Met 99 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18366.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 494.3 | |
| All* | Total formula weight | 18860.9 |
