2K1D
NMR Studies of a Pathogenic Mutant (D178N) of the Human Prion Protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Major prion protein | polymer | 146 | 16492.3 | 1 | UniProt (P04156) Pfam (PF00377) In PDB | Homo sapiens (Human) | PrP, PrP27-30, PrP33-35C, ASCR, CD230 antigen |
Sequence modifications
A: 90 - 231 (UniProt: P04156)
| PDB | External Database | Details |
|---|---|---|
| Gly 86 | - | expression tag |
| Ser 87 | - | expression tag |
| Asp 88 | - | expression tag |
| Pro 89 | - | expression tag |
| Val 129 | Met 129 | variant |
| Asn 178 | Asp 178 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16492.3 | |
| All* | Total formula weight | 16492.3 |
