2JOO

The NMR Solution Structure of Recombinant RGD-hirudin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Hirudin variant-1	polymer	66	7042.6	1	UniProt (P01050) Pfam (PF00713) In PDB	Hirudo medicinalis (medicinal leech)	Lepirudin

Sequence modifications

A: 1 - 66 (UniProt: P01050)

PDB	External Database	Details
Arg 32	Ser 32	engineered mutation
Gly 33	Asp 33	engineered mutation
Asp 34	Gly 34	engineered mutation
Ser 35	Glu 35	engineered mutation
Gln 53	Asp 53	engineered mutation
Pro 58	Glu 58	engineered mutation
Asp 62	Glu 62	engineered mutation
Ala 63	Tyr 63	engineered mutation
Tyr 64	Leu 64	engineered mutation
Asp 65	Gln 65	engineered mutation
Glu 66	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	7042.6
All*	Total formula weight	7042.6

*Water molecules are not included.