2JNR
Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | VIR165 | polymer | 20 | 2241.7 | 1 | synthetic construct | ||
| 2 | B (B) | ENV polyprotein | polymer | 23 | 2125.5 | 1 | UniProt (Q72502) | synthetic construct | FP1-23 |
Sequence modifications
B: 101 - 123 (UniProt: Q72502)
| PDB | External Database | Details |
|---|---|---|
| Arg 122 | Ala 531 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 4367.2 | |
| All* | Total formula weight | 4367.2 |






