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2JNR

Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
VIR165polymer202241.71synthetic construct
2B
(B)
ENV polyproteinpolymer232125.51UniProt (Q72502)synthetic constructFP1-23
Sequence modifications
B: 101 - 123 (UniProt: Q72502)
PDBExternal DatabaseDetails
Arg 122Ala 531engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight4367.2
All*Total formula weight4367.2
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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