2JKO
Focal Adhesion Kinase catalytic domain in complex with bis-anilino pyrimidine inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | FOCAL ADHESION KINASE 1 | polymer | 276 | 31731.8 | 1 | UniProt (Q00944) Pfam (PF07714) In PDB | GALLUS GALLUS (CHICKEN) | PP125FAK |
2 | A | 7-{[(2Z,5S)-5-CHLORO-2-{[2-METHOXY-4-(4-METHYLPIPERAZIN-1-YL)PHENYL]IMINO}-2,5-DIHYDROPYRIMIDIN-4-YL]AMINO}-2-METHYL-2,3-DIHYDRO-1H-ISOINDOL-1-ONE | non-polymer | 494.0 | 1 | Chemie (BIJ) | |||
3 | water | water | 18.0 | 244 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 31731.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 494.0 | |
All* | Total formula weight | 32225.8 |