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2JKO

Focal Adhesion Kinase catalytic domain in complex with bis-anilino pyrimidine inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AFOCAL ADHESION KINASE 1polymer27631731.81UniProt (Q00944)
Pfam (PF07714)
In PDB
GALLUS GALLUS (CHICKEN)PP125FAK
2A7-{[(2Z,5S)-5-CHLORO-2-{[2-METHOXY-4-(4-METHYLPIPERAZIN-1-YL)PHENYL]IMINO}-2,5-DIHYDROPYRIMIDIN-4-YL]AMINO}-2-METHYL-2,3-DIHYDRO-1H-ISOINDOL-1-ONEnon-polymer494.01Chemie (BIJ)
3waterwater18.0244Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31731.8
Non-Polymers*Number of molecules1
Total formula weight494.0
All*Total formula weight32225.8
*Water molecules are not included.

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PDB entries from 2024-08-07

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