2JKH
Factor Xa - cation inhibitor complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ACTIVATED FACTOR XA HEAVY CHAIN | polymer | 241 | 27173.0 | 1 | UniProt (P00742) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | STUART FACTOR, STUART-PROWER FACTOR, COAGULATION FACTOR X |
| 2 | B (L) | FACTOR X LIGHT CHAIN | polymer | 55 | 6060.8 | 1 | UniProt (P00742) Pfam (PF14670) | HOMO SAPIENS (HUMAN) | STUART FACTOR, STUART-PROWER FACTOR, COAGULATION FACTOR X |
| 3 | C (A) | 3-[(3~{a}~{S},4~{R},8~{a}~{S},8~{b}~{R})-4-[5-(5-chloranylthiophen-2-yl)-1,2-oxazol-3-yl]-1,3-bis(oxidanylidene)-4,6,7,8,8~{a},8~{b}-hexahydro-3~{a}~{H}-pyrrolo[3,4-a]pyrrolizin-2-yl]propyl-trimethyl-azanium | non-polymer | 464.0 | 1 | Chemie (BI7) | |||
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | F, G (A, L) | water | water | 18.0 | 410 | Chemie (HOH) |
Sequence modifications
A: 16 - 251 (UniProt: P00742)
| PDB | External Database | Details |
|---|---|---|
| Glu 150 | Arg 372 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33233.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 527.1 | |
| All* | Total formula weight | 33760.9 |
