2JIT
Crystal structure of EGFR kinase domain T790M mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | EPIDERMAL GROWTH FACTOR RECEPTOR | polymer | 327 | 37334.2 | 2 | UniProt (P00533) Pfam (PF07714) In PDB | HOMO SAPIENS (HUMAN) | RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1 |
| 2 | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence modifications
A, B: 696 - 1022 (UniProt: P00533)
| PDB | External Database | Details |
|---|---|---|
| Met 790 | Thr 790 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74668.4 | |
| All* | Total formula weight | 74668.4 |
