2JFA

ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH AN AFFINITY-SELECTED COREPRESSOR PEPTIDE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	ESTROGEN RECEPTOR	polymer	252	28672.5	1	UniProt (P03372) Pfam (PF00104)	HOMO SAPIENS (HUMAN)	ER, ESTRADIOL RECEPTOR, ER-ALPHA, ESTROGEN RECEPTOR ALPHA
2	B (B)	ESTROGEN RECEPTOR	polymer	252	28730.6	1	UniProt (P03372) Pfam (PF00104)	HOMO SAPIENS (HUMAN)	ER, ESTRADIOL RECEPTOR, ER-ALPHA, ESTROGEN RECEPTOR ALPHA
3	C, D (P, Q)	COREPRESSOR PEPTIDE	polymer	16	1903.1	2		SYNTHETIC CONSTRUCT
4	E, H (A, B)	RALOXIFENE	non-polymer		473.6	2	Chemie (RAL)
5	F, G, I, J (A, B)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
6	K, L (A, B)	water	water		18.0	86	Chemie (HOH)

Sequence modifications

A: 282 - 303 (PDB: 2JFA)
A: 304 - 533 (UniProt: P03372)
B: 282 - 303 (PDB: 2JFA)
B: 304 - 533 (UniProt: P03372)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	61209.4
Non-Polymers*	Number of molecules	6
	Total formula weight	1331.4
All*	Total formula weight	62540.8

*Water molecules are not included.