2JEA

Structure of a 9-subunit archaeal exosome bound to RNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	EXOSOME COMPLEX EXONUCLEASE 2	polymer	277	30422.8	1	UniProt (Q9UXC0) Pfam (PF01138) Pfam (PF03725) In PDB	SULFOLOBUS SOLFATARICUS	EXOSOME COMPLEX OF RRP41, RRP42 AND RRP4
2	B	EXOSOME COMPLEX EXONUCLEASE 1	polymer	250	27764.1	1	UniProt (Q9UXC2) Pfam (PF01138) Pfam (PF03725) In PDB	SULFOLOBUS SOLFATARICUS
3	C	RNA	polymer	35	11429.1	1
4	I	EXOSOME COMPLEX RNA-BINDING PROTEIN 1	polymer	251	28225.3	1	UniProt (Q9UXC4) Pfam (PF22625) In PDB	SULFOLOBUS SOLFATARICUS
5	A	PENTAETHYLENE GLYCOL	non-polymer		238.3	1	Chemie (1PE)
6		water	water		18.0	122	Chemie (HOH)

Sequence modifications

A: -1 - 0 (PDB: 2JEA)
A: 1 - 275 (UniProt: Q9UXC0)
B: -1 - 0 (PDB: 2JEA)
B: 1 - 248 (UniProt: Q9UXC2)

PDB	External Database	Details
Ala 182	Asp 182	engineered mutation

I: -1 - 0 (PDB: 2JEA)
I: 1 - 249 (UniProt: Q9UXC4)

PDB	External Database	Details
Glu 8	Lys 8	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	97841.3
Non-Polymers*	Number of molecules	1
	Total formula weight	238.3
All*	Total formula weight	98079.6

*Water molecules are not included.